Publications

Kilic G, Alvarez-Mercado AI, Zarrouki B, Opland D, Liew CWee, Alonso LC, Myers MG, Jonas J-C, Poitout V, Kulkarni RN et al..  2014.  The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.. PLoS One. 9(2):e87941.

Sharma RB, Alonso LC.  2014.  Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well? Curr Diab Rep. 14(6):492.

Behari J, Li H, Liu S, Stefanovic-Racic M, Alonso L, O'Donnell CP, Shiva S, Singamsetty S, Watanabe Y, Singh VP et al..  2014.  β-catenin links hepatic metabolic zonation with lipid metabolism and diet-induced obesity in mice.. Am J Pathol. 184(12):3284-98.

Mordes JP, Alonso LC.  2015.  Evaluation, Medical Therapy, and Course of Adult Persistent Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass Surgery: A Case Series.. Endocr Pract. 21(3):237-46.

Sharma RB, O'Donnell AC, Stamateris RE, Ha B, McCloskey KM, Reynolds PR, Arvan P, Alonso LC.  2015.  Insulin demand regulates β cell number via the unfolded protein response.. J Clin Invest. 125(10):3831-46.

Singamsetty S, Shah FAli, Guo L, Watanabe Y, McDonald S, Sharma R, Zhang Y, Alonso LC, O'Donnell CP, McVerry BJ.  2016.  Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice.. Appl Physiol Nutr Metab. 41(1):12-9.

Stamateris RE, Sharma RB, Kong Y, Ebrahimpour P, Panday D, Ranganath P, Zou B, Levitt H, Parambil NAbraham, O'Donnell CP et al..  2016.  Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.. Diabetes. 65(4):981-95.

Choudhury SR, Fitzpatrick Z, Harris AF, Maitland SA, Ferreira JS, Zhang Y, Ma S, Sharma RB, Gray-Edwards HL, Johnson JA et al..  2016.  In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.. Mol Ther. 24(7):1247-57.

Kong Y, Sharma RB, Nwosu BU, Alonso LC.  2016.  Islet biology, the CDKN2A/B locus and type 2 diabetes risk.. Diabetologia. 59(8):1579-93.

Lakshmipathi J, Alvarez-Perez JCarlos, Rosselot C, Casinelli GP, Stamateris RE, Rausell-Palamos F, O'Donnell CP, Vasavada RC, Scott DK, Alonso LC et al..  2016.  PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.. Diabetes. 65(5):1283-96.

Flach RJRoth, Danai LV, DiStefano MT, Kelly M, Menendez LGarcia, Jurczyk A, Sharma RB, Jung DYoung, Kim JHun, Kim JK et al..  2016.  Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.. J Biol Chem. 291(31):16221-30.

Lundberg RL, Marino KR, Jasrotia A, Maranda LS, Barton BA, Alonso LC, Nwosu BUdoka.  2017.  Partial clinical remission in type 1 diabetes: a comparison of the accuracy of total daily dose of insulin of <0.3 units/kg/day to the gold standard insulin-dose adjusted hemoglobin A1c of ≤9 for the detection of partial clinical remission.. J Pediatr Endocrinol Metab. 30(8):823-830.

Marino KR, Lundberg RL, Jasrotia A, Maranda LS, Thompson MJ, Barton BA, Alonso LC, Nwosu BUdoka.  2017.  A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes.. PLoS One. 12(5):e0176860.

DB H, C WU, N D, IJ S, M S-R, G S, CP O'D, LC A, EE K, EE K et al..  2018.  Adipose Tissue Derived Free Fatty Acids Initiate Myeloid Cell Accumulation in Mouse Liver in States of Lipid Oversupply.. Am J Physiol Endocrinol Metab.

DB H, C WU, N D, IJ S, Stefanovic-Racic M, G S, CP O'D, Alonso LC, EE K, EE K et al..  2018.  Adipose tissue-derived free fatty acids initiate myeloid cell accumulation in mouse liver in states of lipid oversupply..

Nwosu BUdoka, Zhang B, Ayyoub SS, Choi S, Villalobos-Ortiz TR, Alonso LC, Barton BA.  2018.  Children with type 1 diabetes who experienced a honeymoon phase had significantly lower LDL cholesterol 5 years after diagnosis.. PLoS One. 13(5):e0196912.

Kong Y, Hsieh C-H, Alonso LC.  2018.  : A lncRNA at the CDKN2A/B Locus With Roles in Cancer and Metabolic Disease.. Front Endocrinol (Lausanne). 9:405.

Kong Y, Ebrahimpour P, Liu Y, Yang C, Alonso LC.  2018.  Pancreatic Islet Embedding for Paraffin Sections.. J Vis Exp. (136)

Kong Y, Sharma RB, Ly S, Stamateris RE, Jesdale WM, Alonso LC.  2018.  T2D Genome-Wide Association Study Risk SNPs Impact Locus Gene Expression and Proliferation in Human Islets.. Diabetes. 67(5):872-884.

Sharma RB, Snyder JT, Alonso LC.  2019.  Atf6α impacts cell number by influencing survival, death and proliferation.. Mol Metab. 27S:S69-S80.

Sharma RB, Darko C, Zheng X, Gablaski B, Alonso LC.  2019.  DNA Damage Does Not Cause BrdU Labeling of Mouse or Human β-Cells.. Diabetes. 68(5):975-987.

Levasseur EM, Yamada K, Piñeros AR, Wu W, Syed F, Orr KS, Anderson-Baucum E, Mastracci TL, Maier B, Mosley AL et al..  2019.  Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.. Sci Signal. 12(610)

Alonso LC.  2019.  T2D Risk Genes: Exome Sequencing Goes Straight to the Source.. Cell Metab. 30(1):10-11.

Nwosu BUdoka, Yeasmin S, Ayyoub S, Rupendu S, Villalobos-Ortiz TR, Jasmin G, Parajuli S, Zahedi B, Zitek-Morrison E, Alonso LC et al..  2020.  Continuous glucose monitoring reduces pubertal hyperglycemia of type 1 diabetes.. J Pediatr Endocrinol Metab. 33(7):865-872.

Sharma RB, Darko C, Alonso LC.  2020.  Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells.. J Biol Chem. 295(41):14164-14177.