Submitted by asb4002 on February 27, 2020 - 10:36am
Title | T2D Risk Genes: Exome Sequencing Goes Straight to the Source. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Alonso LC |
Journal | Cell Metab |
Volume | 30 |
Issue | 1 |
Pagination | 10-11 |
Date Published | 2019 Jul 02 |
ISSN | 1932-7420 |
Abstract | Genome-wide association studies have identified hundreds of genomic variants associated with human T2D risk, but translating such findings to clinically useful information has proved challenging. A new study in Nature (Flannick et al., 2019) breaks this gridlock, using direct exome sequencing to identify functional coding variants, providing critical complementary gene-level information. |
DOI | 10.1016/j.cmet.2019.06.010 |
Alternate Journal | Cell Metab. |
PubMed ID | 31269421 |
Grant List | R01 DK113300 / DK / NIDDK NIH HHS / United States R01 DK114686 / DK / NIDDK NIH HHS / United States |