Publications

Lundberg RL, Marino KR, Jasrotia A, Maranda LS, Barton BA, Alonso LC, Nwosu BUdoka.  2017.  Partial clinical remission in type 1 diabetes: a comparison of the accuracy of total daily dose of insulin of <0.3 units/kg/day to the gold standard insulin-dose adjusted hemoglobin A1c of ≤9 for the detection of partial clinical remission.. J Pediatr Endocrinol Metab. 30(8):823-830.

Marino KR, Lundberg RL, Jasrotia A, Maranda LS, Thompson MJ, Barton BA, Alonso LC, Nwosu BUdoka.  2017.  A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes.. PLoS One. 12(5):e0176860.

Singamsetty S, Shah FAli, Guo L, Watanabe Y, McDonald S, Sharma R, Zhang Y, Alonso LC, O'Donnell CP, McVerry BJ.  2016.  Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice.. Appl Physiol Nutr Metab. 41(1):12-9.

Stamateris RE, Sharma RB, Kong Y, Ebrahimpour P, Panday D, Ranganath P, Zou B, Levitt H, Parambil NAbraham, O'Donnell CP et al..  2016.  Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.. Diabetes. 65(4):981-95.

Choudhury SR, Fitzpatrick Z, Harris AF, Maitland SA, Ferreira JS, Zhang Y, Ma S, Sharma RB, Gray-Edwards HL, Johnson JA et al..  2016.  In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.. Mol Ther. 24(7):1247-57.

Kong Y, Sharma RB, Nwosu BU, Alonso LC.  2016.  Islet biology, the CDKN2A/B locus and type 2 diabetes risk.. Diabetologia. 59(8):1579-93.

Lakshmipathi J, Alvarez-Perez JCarlos, Rosselot C, Casinelli GP, Stamateris RE, Rausell-Palamos F, O'Donnell CP, Vasavada RC, Scott DK, Alonso LC et al..  2016.  PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.. Diabetes. 65(5):1283-96.

Flach RJRoth, Danai LV, DiStefano MT, Kelly M, Menendez LGarcia, Jurczyk A, Sharma RB, Jung DYoung, Kim JHun, Kim JK et al..  2016.  Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.. J Biol Chem. 291(31):16221-30.

Mordes JP, Alonso LC.  2015.  Evaluation, Medical Therapy, and Course of Adult Persistent Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass Surgery: A Case Series.. Endocr Pract. 21(3):237-46.

Sharma RB, O'Donnell AC, Stamateris RE, Ha B, McCloskey KM, Reynolds PR, Arvan P, Alonso LC.  2015.  Insulin demand regulates β cell number via the unfolded protein response.. J Clin Invest. 125(10):3831-46.

Song W-J, Mondal P, Wolfe A, Alonso LC, Stamateris R, Ong BWT, Lim OC, Yang KS, Radovick S, Novaira HJ et al..  2014.  Glucagon regulates hepatic kisspeptin to impair insulin secretion.. Cell Metab. 19(4):667-81.

Jurczyk A, Bortell R, Alonso LC.  2014.  Human β-cell regeneration: progress, hurdles, and controversy.. Curr Opin Endocrinol Diabetes Obes. 21(2):102-8.

Kilic G, Alvarez-Mercado AI, Zarrouki B, Opland D, Liew CWee, Alonso LC, Myers MG, Jonas J-C, Poitout V, Kulkarni RN et al..  2014.  The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.. PLoS One. 9(2):e87941.

Sharma RB, Alonso LC.  2014.  Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well? Curr Diab Rep. 14(6):492.

Behari J, Li H, Liu S, Stefanovic-Racic M, Alonso L, O'Donnell CP, Shiva S, Singamsetty S, Watanabe Y, Singh VP et al..  2014.  β-catenin links hepatic metabolic zonation with lipid metabolism and diet-induced obesity in mice.. Am J Pathol. 184(12):3284-98.

Stamateris RE, Sharma RB, Hollern DA, Alonso LC.  2013.  Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression.. Am J Physiol Endocrinol Metab. 305(1):E149-59.

Watanabe Y, Singamsetty S, Zou B, Guo L, Stefanovski D, Alonso LC, Garcia-Ocaña A, O'Donnell CP, McVerry BJ.  2013.  Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice.. PLoS One. 8(6):e67716.

Lee EJ, Alonso LC, Stefanovski D, Strollo HC, Romano LC, Zou B, Singamsetty S, Yester KA, McGaffin KR, Garcia-Ocaña A et al..  2013.  Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia.. Eur J Appl Physiol. 113(2):467-78.

Metukuri MR, Zhang P, Basantani MK, Chin C, Stamateris RE, Alonso LC, Takane KK, Gramignoli R, Strom SC, O'Doherty RM et al..  2012.  ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.. Diabetes. 61(8):2004-15.

Pascoe J, Hollern D, Stamateris R, Abbasi M, Romano LC, Zou B, O'Donnell CP, Garcia-Ocaña A, Alonso LC.  2012.  Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18.. Diabetes. 61(3):632-41.

Demirci C, Ernst S, Alvarez-Perez JC, Rosa T, Valle S, Shridhar V, Casinelli GP, Alonso LC, Vasavada RC, Garcia-Ocaña A.  2012.  Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus.. Diabetes. 61(5):1143-52.

Alonso LC, Watanabe Y, Stefanovski D, Lee EJ, Singamsetty S, Romano LC, Zou B, Garcia-Ocaña A, Bergman RN, O'Donnell CP.  2012.  Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled mice.. Obesity (Silver Spring). 20(7):1403-12.

Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC et al..  2011.  Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.. Diabetes. 60(10):2546-59.

Mellado-Gil J, Rosa TC, Demirci C, Gonzalez-Pertusa JA, Velazquez-Garcia S, Ernst S, Valle S, Vasavada RC, Stewart AF, Alonso LC et al..  2011.  Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.. Diabetes. 60(2):525-36.

Levitt HE, Cyphert TJ, Pascoe JL, Hollern DA, Abraham N, Lundell RJ, Rosa T, Romano LC, Zou B, O'Donnell CP et al..  2011.  Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.. Diabetologia. 54(3):572-82.