Publications

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Charbord J, Ren L, Sharma RB, Johansson A, Ågren R, Chu L, Tworus D, Schulz N, Charbord P, Stewart AF et al..  2021.  In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR.. Nat Metab. 3(5):682-700.
Choudhury SR, Fitzpatrick Z, Harris AF, Maitland SA, Ferreira JS, Zhang Y, Ma S, Sharma RB, Gray-Edwards HL, Johnson JA et al..  2016.  In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.. Mol Ther. 24(7):1247-57.
Tchang BG, Askin G, Sahagun A, Hwang J, Huang H, Curanaj FAMendelso, Seley JJ, Safford MM, Alonso LC, Aronne LJ et al..  2021.  The independent risk of obesity and diabetes and their interaction in COVID-19: A retrospective cohort study.. Obesity (Silver Spring).
Sharma RB, O'Donnell AC, Stamateris RE, Ha B, McCloskey KM, Reynolds PR, Arvan P, Alonso LC.  2015.  Insulin demand regulates β cell number via the unfolded protein response.. J Clin Invest. 125(10):3831-46.
Iiyori N, Alonso LC, Li J, Sanders MH, Garcia-Ocaña A, O'Doherty RM, Polotsky VY, O'Donnell CP.  2007.  Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity.. Am J Respir Crit Care Med. 175(8):851-7.
Yokoe T, Alonso LC, Romano LC, Rosa TC, O'Doherty RM, Garcia-Ocaña A, Minoguchi K, O'Donnell CP.  2008.  Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice.. J Physiol. 586(3):899-911.
Sharma RB, Darko C, Alonso LC.  2020.  Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells.. J Biol Chem. 295(41):14164-14177.
Kong Y, Sharma RB, Nwosu BU, Alonso LC.  2016.  Islet biology, the CDKN2A/B locus and type 2 diabetes risk.. Diabetologia. 59(8):1579-93.
Kilic G, Alvarez-Mercado AI, Zarrouki B, Opland D, Liew CWee, Alonso LC, Myers MG, Jonas J-C, Poitout V, Kulkarni RN et al..  2014.  The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.. PLoS One. 9(2):e87941.
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Alonso LC, Rosenfield RL.  2002.  Oestrogens and puberty.. Best Pract Res Clin Endocrinol Metab. 16(1):13-30.