Publications

Levasseur EM, Yamada K, Piñeros AR, Wu W, Syed F, Orr KS, Anderson-Baucum E, Mastracci TL, Maier B, Mosley AL et al..  2019.  Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.. Sci Signal. 12(610)

Stamateris RE, Sharma RB, Kong Y, Ebrahimpour P, Panday D, Ranganath P, Zou B, Levitt H, Parambil NAbraham, O'Donnell CP et al..  2016.  Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.. Diabetes. 65(4):981-95.

Lakshmipathi J, Alvarez-Perez JCarlos, Rosselot C, Casinelli GP, Stamateris RE, Rausell-Palamos F, O'Donnell CP, Vasavada RC, Scott DK, Alonso LC et al..  2016.  PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.. Diabetes. 65(5):1283-96.

Watanabe Y, Singamsetty S, Zou B, Guo L, Stefanovski D, Alonso LC, Garcia-Ocaña A, O'Donnell CP, McVerry BJ.  2013.  Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice.. PLoS One. 8(6):e67716.

Lee EJ, Alonso LC, Stefanovski D, Strollo HC, Romano LC, Zou B, Singamsetty S, Yester KA, McGaffin KR, Garcia-Ocaña A et al..  2013.  Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia.. Eur J Appl Physiol. 113(2):467-78.

Metukuri MR, Zhang P, Basantani MK, Chin C, Stamateris RE, Alonso LC, Takane KK, Gramignoli R, Strom SC, O'Doherty RM et al..  2012.  ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.. Diabetes. 61(8):2004-15.

Pascoe J, Hollern D, Stamateris R, Abbasi M, Romano LC, Zou B, O'Donnell CP, Garcia-Ocaña A, Alonso LC.  2012.  Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18.. Diabetes. 61(3):632-41.

Demirci C, Ernst S, Alvarez-Perez JC, Rosa T, Valle S, Shridhar V, Casinelli GP, Alonso LC, Vasavada RC, Garcia-Ocaña A.  2012.  Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus.. Diabetes. 61(5):1143-52.

Alonso LC, Watanabe Y, Stefanovski D, Lee EJ, Singamsetty S, Romano LC, Zou B, Garcia-Ocaña A, Bergman RN, O'Donnell CP.  2012.  Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled mice.. Obesity (Silver Spring). 20(7):1403-12.

Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC et al..  2011.  Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.. Diabetes. 60(10):2546-59.

Mellado-Gil J, Rosa TC, Demirci C, Gonzalez-Pertusa JA, Velazquez-Garcia S, Ernst S, Valle S, Vasavada RC, Stewart AF, Alonso LC et al..  2011.  Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.. Diabetes. 60(2):525-36.

Woodske ME, Yokoe T, Zou B, Romano LC, Rosa TC, Garcia-Ocaña A, Alonso LC, O'Donnell CP, McVerry BJ.  2009.  Hyperinsulinemia predicts survival in a hyperglycemic mouse model of critical illness.. Crit Care Med. 37(9):2596-603.

Yokoe T, Alonso LC, Romano LC, Rosa TC, O'Doherty RM, Garcia-Ocaña A, Minoguchi K, O'Donnell CP.  2008.  Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice.. J Physiol. 586(3):899-911.

Alonso LC, Yokoe T, Zhang P, Scott DK, Kim SK, O'Donnell CP, Garcia-Ocaña A.  2007.  Glucose infusion in mice: a new model to induce beta-cell replication.. Diabetes. 56(7):1792-801.

Iiyori N, Alonso LC, Li J, Sanders MH, Garcia-Ocaña A, O'Doherty RM, Polotsky VY, O'Donnell CP.  2007.  Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity.. Am J Respir Crit Care Med. 175(8):851-7.