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Laura Alonso, MD
Publications
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Found 52 results
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Alonso, Laura C
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2016
Singamsetty S
,
Shah FAli
,
Guo L
,
Watanabe Y
,
McDonald S
,
Sharma R
,
Zhang Y
,
Alonso LC
,
O'Donnell CP
,
McVerry BJ
. 2016.
Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice.
.
Appl Physiol Nutr Metab. 41(1):12-9.
Stamateris RE
,
Sharma RB
,
Kong Y
,
Ebrahimpour P
,
Panday D
,
Ranganath P
,
Zou B
,
Levitt H
,
Parambil NAbraham
,
O'Donnell CP
et al.
. 2016.
Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.
.
Diabetes. 65(4):981-95.
Choudhury SR
,
Fitzpatrick Z
,
Harris AF
,
Maitland SA
,
Ferreira JS
,
Zhang Y
,
Ma S
,
Sharma RB
,
Gray-Edwards HL
,
Johnson JA
et al.
. 2016.
In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.
.
Mol Ther. 24(7):1247-57.
Kong Y
,
Sharma RB
,
Nwosu BU
,
Alonso LC
. 2016.
Islet biology, the CDKN2A/B locus and type 2 diabetes risk.
.
Diabetologia. 59(8):1579-93.
Lakshmipathi J
,
Alvarez-Perez JCarlos
,
Rosselot C
,
Casinelli GP
,
Stamateris RE
,
Rausell-Palamos F
,
O'Donnell CP
,
Vasavada RC
,
Scott DK
,
Alonso LC
et al.
. 2016.
PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.
.
Diabetes. 65(5):1283-96.
Flach RJRoth
,
Danai LV
,
DiStefano MT
,
Kelly M
,
Menendez LGarcia
,
Jurczyk A
,
Sharma RB
,
Jung DYoung
,
Kim JHun
,
Kim JK
et al.
. 2016.
Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.
.
J Biol Chem. 291(31):16221-30.
2015
Mordes JP
,
Alonso LC
. 2015.
Evaluation, Medical Therapy, and Course of Adult Persistent Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass Surgery: A Case Series.
.
Endocr Pract. 21(3):237-46.
Sharma RB
,
O'Donnell AC
,
Stamateris RE
,
Ha B
,
McCloskey KM
,
Reynolds PR
,
Arvan P
,
Alonso LC
. 2015.
Insulin demand regulates β cell number via the unfolded protein response.
.
J Clin Invest. 125(10):3831-46.
2014
Song W-J
,
Mondal P
,
Wolfe A
,
Alonso LC
,
Stamateris R
,
Ong BWT
,
Lim OC
,
Yang KS
,
Radovick S
,
Novaira HJ
et al.
. 2014.
Glucagon regulates hepatic kisspeptin to impair insulin secretion.
.
Cell Metab. 19(4):667-81.
Jurczyk A
,
Bortell R
,
Alonso LC
. 2014.
Human β-cell regeneration: progress, hurdles, and controversy.
.
Curr Opin Endocrinol Diabetes Obes. 21(2):102-8.
Kilic G
,
Alvarez-Mercado AI
,
Zarrouki B
,
Opland D
,
Liew CWee
,
Alonso LC
,
Myers MG
,
Jonas J-C
,
Poitout V
,
Kulkarni RN
et al.
. 2014.
The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.
.
PLoS One. 9(2):e87941.
Sharma RB
,
Alonso LC
. 2014.
Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well?
Curr Diab Rep. 14(6):492.
2013
Stamateris RE
,
Sharma RB
,
Hollern DA
,
Alonso LC
. 2013.
Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression.
.
Am J Physiol Endocrinol Metab. 305(1):E149-59.
Watanabe Y
,
Singamsetty S
,
Zou B
,
Guo L
,
Stefanovski D
,
Alonso LC
,
Garcia-Ocaña A
,
O'Donnell CP
,
McVerry BJ
. 2013.
Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice.
.
PLoS One. 8(6):e67716.
Lee EJ
,
Alonso LC
,
Stefanovski D
,
Strollo HC
,
Romano LC
,
Zou B
,
Singamsetty S
,
Yester KA
,
McGaffin KR
,
Garcia-Ocaña A
et al.
. 2013.
Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia.
.
Eur J Appl Physiol. 113(2):467-78.
2012
Metukuri MR
,
Zhang P
,
Basantani MK
,
Chin C
,
Stamateris RE
,
Alonso LC
,
Takane KK
,
Gramignoli R
,
Strom SC
,
O'Doherty RM
et al.
. 2012.
ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.
.
Diabetes. 61(8):2004-15.
Pascoe J
,
Hollern D
,
Stamateris R
,
Abbasi M
,
Romano LC
,
Zou B
,
O'Donnell CP
,
Garcia-Ocaña A
,
Alonso LC
. 2012.
Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18.
.
Diabetes. 61(3):632-41.
Demirci C
,
Ernst S
,
Alvarez-Perez JC
,
Rosa T
,
Valle S
,
Shridhar V
,
Casinelli GP
,
Alonso LC
,
Vasavada RC
,
Garcia-Ocaña A
. 2012.
Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus.
.
Diabetes. 61(5):1143-52.
Alonso LC
,
Watanabe Y
,
Stefanovski D
,
Lee EJ
,
Singamsetty S
,
Romano LC
,
Zou B
,
Garcia-Ocaña A
,
Bergman RN
,
O'Donnell CP
. 2012.
Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled mice.
.
Obesity (Silver Spring). 20(7):1403-12.
2011
Velazquez-Garcia S
,
Valle S
,
Rosa TC
,
Takane KK
,
Demirci C
,
Alvarez-Perez JC
,
Mellado-Gil JM
,
Ernst S
,
Scott DK
,
Vasavada RC
et al.
. 2011.
Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.
.
Diabetes. 60(10):2546-59.
Mellado-Gil J
,
Rosa TC
,
Demirci C
,
Gonzalez-Pertusa JA
,
Velazquez-Garcia S
,
Ernst S
,
Valle S
,
Vasavada RC
,
Stewart AF
,
Alonso LC
et al.
. 2011.
Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.
.
Diabetes. 60(2):525-36.
2009
Woodske ME
,
Yokoe T
,
Zou B
,
Romano LC
,
Rosa TC
,
Garcia-Ocaña A
,
Alonso LC
,
O'Donnell CP
,
McVerry BJ
. 2009.
Hyperinsulinemia predicts survival in a hyperglycemic mouse model of critical illness.
.
Crit Care Med. 37(9):2596-603.
2008
Yokoe T
,
Alonso LC
,
Romano LC
,
Rosa TC
,
O'Doherty RM
,
Garcia-Ocaña A
,
Minoguchi K
,
O'Donnell CP
. 2008.
Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice.
.
J Physiol. 586(3):899-911.
2007
Alonso LC
,
Yokoe T
,
Zhang P
,
Scott DK
,
Kim SK
,
O'Donnell CP
,
Garcia-Ocaña A
. 2007.
Glucose infusion in mice: a new model to induce beta-cell replication.
.
Diabetes. 56(7):1792-801.
Iiyori N
,
Alonso LC
,
Li J
,
Sanders MH
,
Garcia-Ocaña A
,
O'Doherty RM
,
Polotsky VY
,
O'Donnell CP
. 2007.
Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity.
.
Am J Respir Crit Care Med. 175(8):851-7.
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